SAA2

Also known as serum amyloid A2, SAA1, SAA

Serum amyloid A protein is a protein that in humans is encoded by the SAA2 gene.

In the Vinony graph

Within Vinony's link graph, SAA2 is referenced by 6 other articles, and connects out to PubMed, human chromosome 11 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 11.

Its subject is documented across 6 Wikipedia language editions.

Gene data

SAA2

Name: serum amyloid A2
Type: protein-coding
Position: 18,238,236–18,248,668 (−)
Aliases: SAA
Ensembl: ENSG00000134339
RefSeq RNA: NM_001127380.3, NM_001385666.1, NM_001385667.1, NM_001385668.1, NM_001385669.1
RefSeq protein: NP_001120852.1, NP_001372595.1, NP_001372596.1, NP_001372597.1, NP_001372598.1

This gene encodes a member of the serum amyloid A family of apolipoproteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a major acute phase protein that is highly expressed in response to inflammation and tissue injury. This protein also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of this protein are associated with chronic inflammatory diseases including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn's disease. This protein may also be a potential biomarker for certain tumors. Finally, antimicrobial activity against S. aureus and E. coli resides in the N-terminal portion of the mature protein. [provided by RefSeq, Jul 2020].