SAFB2
Sign in to saveAlso known as scaffold attachment factor B2
Scaffold attachment factor B2 is a protein that in humans is encoded by the SAFB2 gene.
Gene data
SAFB2- Name
- scaffold attachment factor B2
- Type
- protein-coding
- Position
- 5,586,981–5,624,046 (−)
- Ensembl
- ENSG00000130254
- RefSeq RNA
- NM_014649.3, XM_011528449.4, XM_054322744.1, XM_054322745.1
- RefSeq protein
- NP_055464.1, XP_011526751.1, XP_054178719.1, XP_054178720.1
The protein encoded by this gene, along with its paralog (scaffold attachment factor B1), is a repressor of estrogen receptor alpha. The encoded protein binds scaffold/matrix attachment region (S/MAR) DNA and is involved in cell cycle regulation, apoptosis, differentiation, the stress response, and regulation of immune genes. [provided by RefSeq, May 2016].
Gene Ontology
Biological process
Molecular function
Cellular component
via MyGene.info
Gene · Ensembl
scaffold attachment factor B2
- Symbol
- SAFB2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 19:5,586,981-5,624,046
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 35210
- exact match
- identifiers.org/ncbigene/9667
- genomic end
- 5624057
- genomic start
- 5587010
- cytogenetic location
- 19p13.3
Sources (4)
via Wikidata · CC0
~1 min read
Article
3 sectionsContents
- Interactions
- References
- Further reading
Scaffold attachment factor B2 is a protein that in humans is encoded by the SAFB2 gene.
== Interactions ==