SDCBP2
Sign in to saveAlso known as SITAC, SITAC18, ST-2, syndecan binding protein 2, ST2
Syntenin-2 is a protein that in humans is encoded by the SDCBP2 gene.
Gene data
SDCBP2- Name
- syndecan binding protein 2
- Type
- protein-coding
- Aliases
- SITAC, SITAC18, ST-2, ST2
The protein encoded by this gene contains two class II PDZ domains. PDZ domains facilitate protein-protein interactions by binding to the cytoplasmic C-terminus of transmembrane proteins, and PDZ-containing proteins mediate cell signaling and the organization of protein complexes. The encoded protein binds to phosphatidylinositol 4, 5-bisphosphate (PIP2) and plays a role in nuclear PIP2 organization and cell division. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Read-through transcription also exists between this gene and the upstream FKBP1A (FK506 binding protein 1A, 12kDa) gene, as represented in GeneID:100528031. [provided by RefSeq, Sep 2011].
via MyGene.info
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 9240
- exact match
- identifiers.org/ncbigene/27111
- genomic end
- 1329139
- genomic start
- 1290619
- cytogenetic location
- 20p13
Sources (4)
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Article
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- References
- Further reading
Syntenin-2 is a protein that in humans is encoded by the SDCBP2 gene.
==References==