SDCBP2
Sign in to saveAlso known as SITAC, SITAC18, ST-2, syndecan binding protein 2, ST2
Syntenin-2 is a protein that in humans is encoded by the SDCBP2 gene.
In the Vinony graph
Within Vinony's link graph, SDCBP2 is referenced by 2 other articles, and connects out to PubMed, human chromosome 20 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 20.
Its subject is documented across 5 Wikipedia language editions.
Gene data
SDCBP2- Name
- syndecan binding protein 2
- Type
- protein-coding
- Position
- 1,309,909–1,329,211 (−)
- Aliases
- SITAC, SITAC18, ST-2, ST2
- Ensembl
- ENSG00000125775
- RefSeq RNA
- NM_001199784.2, NM_015685.6, NM_080489.5
- RefSeq protein
- NP_001186713.1, NP_056500.2, NP_536737.3
The protein encoded by this gene contains two class II PDZ domains. PDZ domains facilitate protein-protein interactions by binding to the cytoplasmic C-terminus of transmembrane proteins, and PDZ-containing proteins mediate cell signaling and the organization of protein complexes. The encoded protein binds to phosphatidylinositol 4, 5-bisphosphate (PIP2) and plays a role in nuclear PIP2 organization and cell division. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Read-through transcription also exists between this gene and the upstream FKBP1A (FK506 binding protein 1A, 12kDa) gene, as represented in GeneID:100528031. [provided by RefSeq, Sep 2011].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
syndecan binding protein 2
- Symbol
- SDCBP2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 20:1,309,909-1,329,211
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 9240
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/27111
- genomic end
- 1329139
- genomic start
- 1290619
- chromosome
- human chromosome 20
- cytogenetic location
- 20p13
- expressed in
- duodenum
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Syntenin-2 is a protein that in humans is encoded by the SDCBP2 gene.
==References==
Excerpted from Wikipedia’s “SDCBP2” article, available under the CC BY-SA 4.0 licence.