SEC24D
Sign in to saveAlso known as CLCRP2, SEC24 homolog D, COPII coat complex component
Protein transport protein Sec24D is a protein that in humans is encoded by the SEC24D gene.
In the Vinony graph
Vinony's link graph records 5 inbound references to SEC24D, and connects out to PubMed, human chromosome 4 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 4.
Vinony links it to 7 Wikipedia language editions.
Gene data
SEC24D- Name
- SEC24 homolog D, COPII component
- Type
- protein-coding
- Position
- 118,722,572–118,838,683 (−)
- Aliases
- CLCRP2
- Ensembl
- ENSG00000150961
- RefSeq RNA
- NM_001318066.2, NM_014822.4
- RefSeq protein
- NP_001304995.1, NP_055637.2
The protein encoded by this gene is a member of the SEC24 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec24p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. This gene product is implicated in the shaping of the vesicle, and also in cargo selection and concentration. Mutations in this gene have been associated with Cole-Carpenter syndrome, a disorder affecting bone formation, resulting in craniofacial malformations and bones that break easily. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
SEC24 homolog D, COPII component
- Symbol
- SEC24D
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 4:118,722,572-118,838,683
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein SEC24D PDB 3EFO.png
Show 8 more facts
- HomoloGene ID
- 40986
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/9871
- genomic end
- 119759838
- genomic start
- 119643978
- chromosome
- human chromosome 4
- cytogenetic location
- 4q26
- expressed in
- tibia
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Protein transport protein Sec24D is a protein that in humans is encoded by the SEC24D gene.
The protein encoded by this gene is a member of the SEC24 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec24p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The role of this gene product is implicated in the shaping of the vesicle, and also in cargo selection and concentration.
Excerpted from Wikipedia’s “SEC24D” article, available under the CC BY-SA 4.0 licence.