SEC24D
Sign in to saveAlso known as CLCRP2, SEC24 homolog D, COPII coat complex component
Protein transport protein Sec24D is a protein that in humans is encoded by the SEC24D gene.
Gene data
SEC24D- Name
- SEC24 homolog D, COPII component
- Type
- protein-coding
- Aliases
- CLCRP2
The protein encoded by this gene is a member of the SEC24 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec24p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. This gene product is implicated in the shaping of the vesicle, and also in cargo selection and concentration. Mutations in this gene have been associated with Cole-Carpenter syndrome, a disorder affecting bone formation, resulting in craniofacial malformations and bones that break easily. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015].
via MyGene.info
Wikidata facts
- Image
- Protein SEC24D PDB 3EFO.png
Show 5 more facts
- HomoloGene ID
- 40986
- exact match
- identifiers.org/ncbigene/9871
- genomic end
- 119759838
- genomic start
- 119643978
- cytogenetic location
- 4q26
Sources (4)
via Wikidata · CC0
~1 min read
Article
2 sectionsContents
- References
- Further reading
Protein transport protein Sec24D is a protein that in humans is encoded by the SEC24D gene.
The protein encoded by this gene is a member of the SEC24 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec24p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The role of this gene product is implicated in the shaping of the vesicle, and also in cargo selection and concentration.