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سلانک

Structure via PubChem · Public domain (PubChem)

EntityQ5810370· pop 8· linked from 920 articles

سلانک

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Also known as selanc

Selank (Russian: Cеланк) is a nootropic anxiolytic peptide based drug developed by the Institute of Molecular Genetics of the Russian Academy of Sciences. Selank is a heptapeptide with the sequence Thr-Lys-Pro-Arg-Pro-Gly-Pro (TKPRPGP). It is a synthetic analogue of the human tuftsin. It was initially developed to modulate brain activity and the immune system and may help regulate neurotransmitters like serotonin and dopamine to promote cognitive stability and emotional balance.

Chemical data

Formula
C33H57N11O9
Molecular weight
751.9 g/mol
IUPAC name
(2S)-1-[2-[[(2S)-1-[(2S)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S,3R)-2-amino-3-hydroxybutanoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]acetyl]pyrrolidine-2-carboxylic acid
SMILES
C[C@H]([C@@H](C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)N2CCC[C@H]2C(=O)NCC(=O)N3CCC[C@H]3C(=O)O)N)O
InChIKey
JTDTXGMXNXBGBZ-YVHUGQOKSA-N
XLogP
-6.1
Polar surface area
322 Ų
H-bond donors
9
H-bond acceptors
12
Formal charge
0

via PubChem

Wikidata facts

Mass
751.4340724040001
Show 4 more facts
subject has role
nootropic
chemical formula
C₃₃H₅₇N₁₁O₉
canonical SMILES
CC(O)C(N)C(O)=NC(CCCCN)C(=O)N1CCCC1C(O)=NC(CCCNC(=N)N)C(=O)N1CCCC1C(O)=NCC(=O)N1CCCC1C(=O)O
isomeric SMILES
C[C@@H](O)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N1CCC[C@H]1C(=O)O
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