selectin P
Sign in to saveP-selectin is a type-1 transmembrane protein that in humans is encoded by the SELP gene.
Wikidata facts
- Instance of
- protein
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- P681
- plasma membrane
- P703
- Homo sapiens
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Article
10 sectionsContents
- Gene and regulation
- Structure
- Ligand
- Function
- Role in cancer
- As a drug target
- See also
- References
- Further reading
- External links
P-selectin is a type-1 transmembrane protein that in humans is encoded by the SELP gene.
P-selectin functions as a cell adhesion molecule (CAM) on the surfaces of activated endothelial cells, which line the inner surface of blood vessels, and activated platelets. In unactivated endothelial cells, it is stored in granules called Weibel-Palade bodies. In unactivated platelets P-selectin is stored in α-granules.