سلکتین
Sign in to saveAlso known as selectins, Selectin, C-type lectin-like domain, protein family, IPR033991
The selectins (cluster of differentiation 62 or CD62) are a family of cell adhesion molecules (or CAMs). All selectins are single-chain transmembrane glycoproteins that share similar properties to C-type lectins due to a related amino terminus and calcium-dependent binding. Selectins bind to sugar moieties and so are considered to be a type of lectin, cell adhesion proteins that bind sugar polymers.
Key facts
- Protein family.Symbol
- Selectin
- Protein family.Name
- Selectin
- Protein family.image
- Pselectin.PNG
- Protein family.width
- 200px
- Protein family.caption
- Crystallographic structure of P-selectin lectin bound to sugar, shown in sticks.
- Protein family.InterPro
- IPR002396
- Protein family.Membranome superfamily
- 12
via Wikipedia infobox
Research
26,679 papers- Selectin-Mediated Signaling-Shedding Light on the Regulation of Integrin Activity in Neutrophils.Cells · 2022
- P-selectin glycoprotein ligand-1 in T cells.Current opinion in hematology · 2017
- P- and E- selectin in venous thrombosis and non-venous pathologies.Journal of thrombosis and haemostasis : JTH · 2022
- Selectin-carbohydrate interactions during inflammation and metastasis.Glycoconjugate journal · 1997
- Selectin antagonists : therapeutic potential in asthma and COPD.Treatments in respiratory medicine · 2005
via PubMed