Simfibrate (JAN/INN; trade name Cholesolvin) is a fibrate that has been used for the treatment of hyperlipidemia. The substance is a double ester of clofibric acid with 1,3-propanediol which is cleaved in the body to one molecule of 1,3-propanediol and two molecules of clofibric acid which is the true lipid-lowering agent.
{{Drugbox | Watchedfields = changed | verifiedrevid = 464391792 | IUPAC_name = Propane-1,3-diyl bis[2-(4-chlorophenoxy)-2-methylpropanoate] | image = Simfibrate.svg | image_class = skin-invert-image
| tradename = Cholesolvin | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration =
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).