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telmisartan

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EntityQ733186· pop 29· linked from 311 articles

telmisartan

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Also known as BIBR-277SE, Micardis®, Pritor®, 4'-((1,4'-dimethyl-2'-propyl(2,6'-bi-1H-benzimidazol)-1'-yl)methyl)-(1,1'-biphenyl)-2-carboxylic acid, 4'-((4-methyl-6-(1-methyl-2-benzimidazolyl)-2-propyl-1-benzimidazolyl)methyl)-2-biphenylcarboxylic acid, BIBR 277, 4'-[(1,7'-dimethyl-2'-propyl-1H,3'H-2,5'-bibenzimidazol-3'-yl)methyl]biphenyl-2-carboxylic acid, 4'-[(1,4'-dimethyl-2'propyl[2,6'-bi-1H-benzimidazol]-1'-yl)methyl]-[1,1'-biphenyl]-2-carboxylic acid

Telmisartan, sold under the brand name Micardis among others, is a medication used to treat high blood pressure and heart failure. It is a reasonable initial treatment for high blood pressure. It is taken by mouth.

In the Vinony graph

Within Vinony's link graph, telmisartan is referenced by 311 other articles, and connects out to angiotensins, amlodipine/valsartan and kidney failure.

It sits within the topics Angiotensin II receptor antagonists, Benzimidazoles and Benzoic acids.

Its subject is documented across 28 Wikipedia language editions.

Key facts

Drug.Watchedfields
changed
Drug.verifiedrevid
477861448
Drug.image
Telmisartan.svg
Drug.image_class
skin-invert-image
Drug.width
220
Drug.tradename
Micardis, others
Drug.MedlinePlus
a601249
Drug.DailyMedID
Telmisartan
Drug.pregnancy_AU
D
Drug.pregnancy_category
Not recommended
Drug.routes_of_administration
By mouth
Drug.class
Angiotensin II receptor antagonist
Drug.ATC_prefix
C09
Drug.ATC_suffix
CA07
Drug.legal_AU
S4
Drug.legal_CA
Rx-only
Drug.legal_UK
POM
Drug.legal_US
Rx-only

via Wikipedia infobox

Chemical data

Formula
C33H30N4O2
Molecular weight
514.6 g/mol
IUPAC name
2-[4-[[4-methyl-6-(1-methylbenzimidazol-2-yl)-2-propylbenzimidazol-1-yl]methyl]phenyl]benzoic acid
SMILES
CCCC1=NC2=C(N1CC3=CC=C(C=C3)C4=CC=CC=C4C(=O)O)C=C(C=C2C)C5=NC6=CC=CC=C6N5C
InChIKey
RMMXLENWKUUMAY-UHFFFAOYSA-N
XLogP
6.9
Polar surface area
72.9 Ų
H-bond donors
1
H-bond acceptors
4
Formal charge
0

via PubChem

Research

3,150 papers

via PubMed

Wikidata facts

Mass
514.237
Show 5 more facts
chemical formula
C₃₃H₃₀N₄O₂
canonical SMILES
CCCC1=NC2=C(C=C(C=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C(=O)O)C5=NC6=CC=CC=C6N5C)C
World Health Organisation international non-proprietary name
telmisartan
defined daily dose
40
Commons category
Telmisartan
Sources (7)

via Wikidata · CC0

~8 min read

Encyclopedic overview

12 sections
Contents
  • Medical uses
  • Contraindications
  • Side effects
  • Interactions
  • Pharmacology
  • Mechanism of action
  • Pharmacokinetics
  • History
  • Society and culture
  • Research
  • References
  • Further reading

{{Infobox drug | Watchedfields = changed | verifiedrevid = 477861448 | image = Telmisartan.svg | image_class = skin-invert-image | width = 220 | alt =

| pronounce = | tradename = Micardis, others | Drugs.com = | MedlinePlus = a601249 | DailyMedID = Telmisartan | pregnancy_AU = D | pregnancy_AU_comment = | pregnancy_category = Not recommended | routes_of_administration = By mouth | class = Angiotensin II receptor antagonist | ATC_prefix = C09 | ATC_suffix = CA07 | ATC_supplemental =

Excerpted from Wikipedia’s “telmisartan” article, available under the CC BY-SA 4.0 licence.

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