SLC18A1
Sign in to saveAlso known as CGAT, VAT1, VMAT1, Vesicular monoamine transporter 1, solute carrier family 18 member A1, VMAT2
protein-coding gene in the species Homo sapiens
Gene data
SLC18A1- Name
- solute carrier family 18 member A1
- Type
- protein-coding
- Aliases
- CGAT, VAT1, VMAT1
The vesicular monoamine transporter acts to accumulate cytosolic monoamines into vesicles, using the proton gradient maintained across the vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine (Peter et al., 1993 [PubMed 7905859]). See also SLC18A2 (MIM 193001).[supplied by OMIM, Mar 2008].
via MyGene.info
Gene · Ensembl
solute carrier family 18 member A1
- Symbol
- SLC18A1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 8:20,144,186-20,183,206
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 20664
- exact match
- identifiers.org/ncbigene/6570
- genomic end
- 20040717
- genomic start
- 20002366
- cytogenetic location
- 8p21.3
Sources (4)
via Wikidata · CC0