SLC25A14

Also known as solute carrier family 25 (mitochondrial carrier, brain), member 14, BMCP1, UCP5, solute carrier family 25 member 14

protein-coding gene in the species Homo sapiens

In the Vinony graph

Vinony's link graph records 258 inbound references to SLC25A14, and connects out to Q180686, Ensembl genome database project and transmembrane transport proteins.

Vinony files it under Genes on human chromosome X and Solute carrier family.

Vinony links it to 5 Wikipedia language editions.

Gene data

SLC25A14

Name: solute carrier family 25 member 14
Type: protein-coding
Chromosome: X
Position: 130,339,886–130,373,453 (+)
Aliases: BMCP1, UCP5
Ensembl: ENSG00000102078
RefSeq RNA: NM_001282195.2, NM_001282196.2, NM_001282197.2, NM_001282198.2, NM_003951.2
RefSeq protein: NP_001269124.1, NP_001269125.1, NP_001269126.1, NP_001269127.1, XP_005262546.1

Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). Uncoupling proteins separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. Uncoupling proteins facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. This gene is widely expressed in many tissues with the greatest abundance in brain and testis. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on chromosome 4. [provided by RefSeq, Aug 2013].