SLC1A2

Name

solute carrier family 1 member 2

Type

protein-coding

Position

35,251,205–35,420,063 (−)

Aliases

DEE41, EAAT2, EIEE41, GLT-1, GLT1, HBGT

Ensembl

ENSG00000110436

RefSeq RNA

NM_001195728.3, NM_001252652.2, NM_001439341.1, NM_001439342.1, NM_001439343.1

RefSeq protein

NP_001182657.1, NP_001239581.1, NP_001426270.1, NP_001426271.1, NP_001426272.1

This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Improper regulation of this gene is thought to be associated with several neurological disorders. Alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Jun 2017].

via MyGene.info

Gene · Ensembl

solute carrier family 1 member 2

Symbol

SLC1A2

Biotype

Protein coding

Organism

Homo sapiens

Location

11:35,251,205-35,420,063

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

via Wikidata · CC0