SNCG
Sign in to saveAlso known as BCSG1, SR, synuclein gamma
Gamma-synuclein is a protein that in humans is encoded by the SNCG gene.
Gene data
SNCG- Name
- synuclein gamma
- Type
- protein-coding
- Position
- 86,955,753–86,963,264 (+)
- Aliases
- BCSG1, SR
- Ensembl
- ENSG00000173267
- RefSeq RNA
- NM_001330120.2, NM_003087.3, XM_047425681.1, XM_054366646.1, XM_054366647.1
- RefSeq protein
- NP_001317049.1, NP_003078.2, XP_047281637.1, XP_054222621.1, XP_054222622.1
This gene encodes a member of the synuclein family of proteins which are believed to be involved in the pathogenesis of neurodegenerative diseases. Mutations in this gene have also been associated with breast tumor development. [provided by RefSeq, Jan 2010].
Gene Ontology
Biological process
Molecular function
Cellular component
via MyGene.info
Gene · Ensembl
synuclein gamma
- Symbol
- SNCG
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 10:86,955,753-86,963,264
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
4 sectionsContents
- Interactions
- See also
- References
- Further reading
Gamma-synuclein is a protein that in humans is encoded by the SNCG gene.
Synuclein-gamma is a member of the synuclein family of proteins, which are believed to be involved in the pathogenesis of neurodegenerative diseases. High levels of SNCG have been identified in advanced breast carcinomas suggesting a correlation between overexpression of SNCG and breast tumor development. Gamma-synuclein is a synuclein protein found primarily in the peripheral nervous system (in primary sensory neurons, sympathetic neurons, and motor neurons) and retina. It is also detected in the brain, ovarian tumors, and in the olfactory epithelium. Gamma-synuclein is the least conserved of the synuclein proteins.
Excerpted from Wikipedia’s “SNCG” article, available under the CC BY-SA 4.0 licence.