Spiramycin

Chemical data

Formula

C43H74N2O14

Molecular weight

843.1 g/mol

IUPAC name

2-[(4R,5S,6S,7R,9R,10R,11E,13E,16R)-6-[(2S,3R,4R,5S,6R)-5-[(2S,4R,5S,6S)-4,5-dihydroxy-4,6-dimethyloxan-2-yl]oxy-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-10-[(2R,5S,6S)-5-(dimethylamino)-6-methyloxan-2-yl]oxy-4-hydroxy-5-methoxy-9,16-dimethyl-2-oxo-1-oxacyclohexadeca-11,13-dien-7-yl]acetaldehyde

SMILES

C[C@@H]1C/C=C/C=C/[C@@H]([C@@H](C[C@@H]([C@@H]([C@H]([C@@H](CC(=O)O1)O)OC)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)C)O[C@H]3C[C@@]([C@H]([C@@H](O3)C)O)(C)O)N(C)C)O)CC=O)C)O[C@H]4CC[C@@H]([C@@H](O4)C)N(C)C

InChIKey

ACTOXUHEUCPTEW-KWBWCIJSSA-N

XLogP

2.1

Polar surface area

195 Ų

H-bond donors

4

H-bond acceptors

16

Formal charge

0

via PubChem

• Spiramycin renaissance.The Journal of antimicrobial chemotherapy · 1998
• [Spiramycin].Casopis lekaru ceskych · 1994
• SPIRAMYCIN.Canadian Medical Association journal · 1958
• SPIRAMYCIN.British medical journal · 1956
• Pharmacodynamics and pharmacokinetics of spiramycin and their clinical significance.Clinical pharmacokinetics · 1998

via PubMed