استروئید سولفاتاز
Also known as ARSC, ARSC2, ARSC1, ASC, ES, SSDD, XLI, Steroid sulfatase (microsomal), isozyme S
protein-coding gene in the species Homo sapiens
Gene data
STS- Name
- steroid sulfatase
- Type
- protein-coding
- Chromosome
- X
- Aliases
- ARSC, ARSC1, ASC, ES, SSDD, XLI
This gene encodes a multi-pass membrane protein that is localized to the endoplasmic reticulum. It belongs to the sulfatase family and hydrolyzes several 3-beta-hydroxysteroid sulfates, which serve as metabolic precursors for estrogens, androgens, and cholesterol. Mutations in this gene are associated with X-linked ichthyosis (XLI). Alternatively spliced transcript variants resulting from the use of different promoters have been described for this gene (PMID:17601726). [provided by RefSeq, Mar 2016].
via MyGene.info