sulfatase
Sign in to saveAlso known as sulphuric ester hydrolase, sulfatases
In biochemistry, sulfatases are a class of enzymes of the esterase class that catalyze the hydrolysis of sulfate esters into an alcohol and a bisulfate:
In the Vinony graph
Vinony's link graph records 510 inbound references to sulfatase, and connects out to iduronate-2-sulfatase, glycolipid and sulfate.
It is catalogued under the topic Transmembrane proteins.
Vinony links it to 10 Wikipedia language editions.
Research
9,633 papers- Estrogen sulfatase.Methods in enzymology · 2005
- Multiple Sulfatase Deficiency: A Disease Comprising Mucopolysaccharidosis, Sphingolipidosis, and More Caused by a Defect in Posttranslational Modification.International journal of molecular sciences · 2020
- The sulfatase gene family.Current opinion in genetics & development · 1997
- Sulfatase activities towards the regulation of cell metabolism and signaling in mammals.Cellular and molecular life sciences : CMLS · 2010
- Multiple sulfatase deficiency.Neurology · 1988
via PubMed
Wikidata facts
- Subclass of
- esterase
- Image
- 1p49 opm.png
Show 2 more facts
- topic's main category
- Category:EC 3.1.6
- Commons category
- EC 3.1.6
Sources (2)
via Wikidata · CC0
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Encyclopedic overview
5 sectionsContents
- Occurrence and importance
- Three-dimensional structure
- Human proteins containing this domain
- References
- External links
In biochemistry, sulfatases are a class of enzymes of the esterase class that catalyze the hydrolysis of sulfate esters into an alcohol and a bisulfate: \ce{R-OSO3 + H2O} \quad \xrightarrow[\text{sulfatase}]{} \quad \ce{R-OH + HSO4-}
These may be found on a range of substrates, including steroids, carbohydrates and proteins. Sulfate esters may be formed from various alcohols and amines. In the latter case the resultant N-sulfates can also be termed sulfamates.
Excerpted from Wikipedia’s “sulfatase” article, available under the CC BY-SA 4.0 licence.