sulfatase
In biochemistry, sulfatases are a class of enzymes of the esterase class that catalyze the hydrolysis of sulfate esters into an alcohol and a bisulfate:
Research
9,633 papers- Estrogen sulfatase.Methods in enzymology · 2005
- Multiple Sulfatase Deficiency: A Disease Comprising Mucopolysaccharidosis, Sphingolipidosis, and More Caused by a Defect in Posttranslational Modification.International journal of molecular sciences · 2020
- The sulfatase gene family.Current opinion in genetics & development · 1997
- Sulfatase activities towards the regulation of cell metabolism and signaling in mammals.Cellular and molecular life sciences : CMLS · 2010
- Multiple sulfatase deficiency.Neurology · 1988
via PubMed
Article
5 sectionsContents
- Occurrence and importance
- Three-dimensional structure
- Human proteins containing this domain
- References
- External links
In biochemistry, sulfatases are a class of enzymes of the esterase class that catalyze the hydrolysis of sulfate esters into an alcohol and a bisulfate: \ce{R-OSO3 + H2O} \quad \xrightarrow[\text{sulfatase}]{} \quad \ce{R-OH + HSO4-}
These may be found on a range of substrates, including steroids, carbohydrates and proteins. Sulfate esters may be formed from various alcohols and amines. In the latter case the resultant N-sulfates can also be termed sulfamates.