sulfamethizole

Chemical data

Formula

C9H10N4O2S2

Molecular weight

270.3 g/mol

IUPAC name

4-amino-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide

SMILES

CC1=NN=C(S1)NS(=O)(=O)C2=CC=C(C=C2)N

InChIKey

VACCAVUAMIDAGB-UHFFFAOYSA-N

XLogP

0.5

Polar surface area

135 Ų

H-bond donors

2

H-bond acceptors

7

Formal charge

0

via PubChem

Drug data · ChEMBL

Max clinical phase

Approved

Molecule type

Small molecule

First approval

1953

Admin. routes

oral

Indications

osteomyelitis, bacterial disease, eye infection

via ChEMBL · EBI

• Sulfamethizole attenuates poloxamer 407-induced atherosclerotic neointima formation via inhibition of mTOR in C57BL/6 mice.Journal of biochemical and molecular toxicology · 2023
• Sulfamethizole Attenuates Pentylenetetrazole-Induced Seizures in Mice via mTOR Inhibition.Drug development research · 2025
• Photocatalytic degradation of antibiotic sulfamethizole by visible light activated perovskite LaZnO(3).Journal of environmental sciences (China) · 2024
• Sulfamethizole capsule method. A new method for assessing gastric emptying of solids.Digestive diseases and sciences · 1994
• Adsorption and Release of Sulfamethizole from Mesoporous Silica Nanoparticles Functionalised with Triethylenetetramine.International journal of molecular sciences · 2021

via PubMed

Wikidata facts

Subclass of

thiadiazoles

Mass

270.024518

Has use

medication

via Wikidata · CC0