TBXT

Name

T-box transcription factor T

Type

protein-coding

Position

166,157,656–166,168,815 (−)

Aliases

SAVA, T, TFT

Ensembl

ENSG00000164458

RefSeq RNA

NM_001270484.2, NM_001366285.2, NM_001366286.2, NM_003181.4, XM_047419269.1

RefSeq protein

NP_001257413.1, NP_001353214.1, NP_001353215.1, NP_003172.1, XP_047275225.1

The protein encoded by this gene is an embryonic nuclear transcription factor that binds to a specific DNA element, the palindromic T-site. It binds through a region in its N-terminus, called the T-box, and effects transcription of genes required for mesoderm formation and differentiation. The protein is localized to notochord-derived cells. Variation in this gene was associated with susceptibility to neural tube defects and chordoma. A mutation in this gene was found in a family with sacral agenesis with vertebral anomalies. [provided by RefSeq, Sep 2018].

via MyGene.info

Gene · Ensembl

T-box transcription factor T

Symbol

TBXT

Biotype

Protein coding

Organism

Homo sapiens

Location

6:166,157,656-166,168,815

Strand

Reverse (−)

Assembly

GRCh38