telithromycine

Chemical data

Formula

C43H65N5O10

Molecular weight

812 g/mol

IUPAC name

(1S,2R,5R,7R,8R,9R,11R,13R,14R)-8-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-9-methoxy-1,5,7,9,11,13-hexamethyl-15-[4-(4-pyridin-3-ylimidazol-1-yl)butyl]-3,17-dioxa-15-azabicyclo[12.3.0]heptadecane-4,6,12,16-tetrone

SMILES

CC[C@@H]1[C@@]2([C@@H]([C@H](C(=O)[C@@H](C[C@@]([C@@H]([C@H](C(=O)[C@H](C(=O)O1)C)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)(C)OC)C)C)N(C(=O)O2)CCCCN4C=C(N=C4)C5=CN=CC=C5)C

InChIKey

LJVAJPDWBABPEJ-PNUFFHFMSA-N

XLogP

4.2

Polar surface area

172 Ų

H-bond donors

1

H-bond acceptors

13

Formal charge

0

via PubChem

Drug data · ChEMBL

Max clinical phase

Approved

Molecule type

Small molecule

First approval

2001

Admin. routes

oral

Indications

infection, pneumonia, Otitis media, maxillary sinusitis

via ChEMBL · EBI

• Telithromycin.Drugs · 2004
• Telithromycin.Expert review of anti-infective therapy · 2004
• [Telithromycin].Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2004
• Telithromycin.Drugs · 2001
• Telithromycin.Annals of internal medicine · 2006

via PubMed

Wikidata facts

Subclass of

ketolides

Mass

811.473

Has use

medication

via Wikidata · CC0