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terconazole
EntityQ7701687· pop 13· linked from 326 articles

terconazole

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Also known as Triaconazole, Terazol, Terazol 7, Panlomyc, Terazol 3, Fungistat, R-42470, Gyno-Terazol

Terconazole is an antifungal drug used to treat vaginal yeast infection. It comes as a lotion or a suppository and disrupts the biosynthesis of fats in a yeast cell. It has a relatively broad spectrum compared to azole compounds but not triazole compounds. Testing shows that it is a suitable compound for prophylaxis for those that suffer from chronic vulvovaginal candidiasis.

Wikidata facts

Subclass of
azole
Mass
531.180395
Has use
medication
Show 7 more facts
chemical formula
C₂₆H₃₁Cl₂N₅O₃
medical condition treated
vulvovaginal candidiasis
isomeric SMILES
CC(C)N1CCN(CC1)C2=CC=C(C=C2)OC[C@H]3CO[C@](O3)(CN4C=NC=N4)C5=C(C=C(C=C5)Cl)Cl
canonical SMILES
CC(C)N1CCN(CC1)C2=CC=C(C=C2)OCC3COC(O3)(CN4C=NC=N4)C5=C(C=C(C=C5)Cl)Cl
defined daily dose
80
subject has role
antifungal
Commons category
Terconazole
Sources (5)

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Encyclopedic overview

10 sections
Contents
  • Medical uses
  • Side effects
  • Interactions
  • Chemistry
  • Mechanism of action
  • Metabolism
  • History
  • Available forms
  • References
  • External links

Terconazole is an antifungal drug used to treat vaginal yeast infection. It comes as a lotion or a suppository and disrupts the biosynthesis of fats in a yeast cell. It has a relatively broad spectrum compared to azole compounds but not triazole compounds. Testing shows that it is a suitable compound for prophylaxis for those that suffer from chronic vulvovaginal candidiasis.

==Medical uses== Terconazole is approved to treat vulvovaginal candidiasis (vaginal thrush). It works as a broad spectrum antifungal and has shown to be an effective first-line treatment against other Candida species. It also shows effectiveness against dermatomycoses in animal models.

Excerpted from Wikipedia’s “terconazole” article, available under the CC BY-SA 4.0 licence.

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