File:Thyroxine2.svg · Wikimedia Commons · See Wikimedia Commons
ثيروكسين
Sign in to saveAlso known as DL-thyroxine
Thyroxine, also known as T4, is a hormone produced by the thyroid gland. It is the primary form of thyroid hormone found in the blood and acts as a prohormone of the more active thyroid hormone, triiodothyronine (T3). Thyroxine and its active metabolites are essential for regulating metabolic rate, supporting heart and muscle function, promoting brain development, and maintaining bone health.
OverviewAI-generated
Thyroxine is a chemical compound with the formula C₁₅H₁₁I₄NO₄. Its IUPAC name is 2-azaniumyl-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoate. The molecule has a mass of 776.686699832 and a weight of 776.87. It possesses a charge of 0, an xlogp of 3, and a topological polar surface area of 97.2. The structure includes two hydrogen bond donors and four hydrogen bond acceptors.
The compound is associated with a PubMed query count of 66778. It is referenced by 370 other encyclopedia articles.
Synthesized by Vinony from 17 facts across 4 sources: Wikidata, PubMed, PubChem, Vinony graph. Generated from structured data (not the Wikipedia text) and checked against those facts — may still contain errors.
Chemical data
- Formula
- C15H11I4NO4
- Molecular weight
- 776.87 g/mol
- IUPAC name
- 2-azaniumyl-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoate
- SMILES
- C1=C(C=C(C(=C1I)OC2=CC(=C(C(=C2)I)O)I)I)CC(C(=O)[O-])[NH3+]
- InChIKey
- XUIIKFGFIJCVMT-UHFFFAOYSA-N
- XLogP
- 3
- Polar surface area
- 97.2 Ų
- H-bond donors
- 2
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Research
66,778 papers- Thyroxine's evolutionary roots.Perspectives in biology and medicine · 1997
- A short review on the role of thyroxine in fast wound healing and tissue regeneration.Tissue & cell · 2023
- DIETARY thyroxine and hypothyroidism.Nutrition reviews · 1953
- Recent developments with thyroxine.The Pharmaceutical journal · 1949
- A bivariate reference interval for TSH and free thyroxine.Scandinavian journal of clinical and laboratory investigation · 2024
via PubMed
Article · العربية
الثيروكسين (بالإنجليزية: Thyroxin, Tetraiodothyronine, T4) هو هرمون تنتجه الخلايا الجريبية في الغدة الدرقية وتفرزه في مجرى الدم. وهو الهرمون الأساسي للغدة الدرقية وضروري لعمليات الأيض والنمو.
Abstract from DBpedia / Wikipedia · CC BY-SA