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GeneQ18037216· pop 6· linked from 492 articles

TNFRSF13B

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Also known as CD267, CVID, CVID2, RYZN, TACI, TNFRSF14B, IGAD2, tumor necrosis factor receptor superfamily member 13B

protein-coding gene in the species Homo sapiens

Gene data

TNFRSF13B
Name
TNF receptor superfamily member 13B
Type
protein-coding
Position
16,929,816–16,972,118 (−)
Aliases
CD267, CVID, CVID2, IGAD2, RYZN, TACI, TNFRSF14B
Ensembl
ENSG00000240505
RefSeq RNA
NM_012452.3
RefSeq protein
NP_036584.1

The protein encoded by this gene is a lymphocyte-specific member of the tumor necrosis factor (TNF) receptor superfamily. It interacts with calcium-modulator and cyclophilin ligand (CAML). The protein induces activation of the transcription factors NFAT, AP1, and NF-kappa-B and plays a crucial role in humoral immunity by interacting with a TNF ligand. This gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008].

Gene Ontology

Pathways

Cytokine-cytokine receptor interaction - Homo sapiens (human)Intestinal immune network for IgA production - Homo sapiens (human)Primary immunodeficiency - Homo sapiens (human)Cytokine Signaling in Immune systemImmune SystemTNFR2 non-canonical NF-kB pathwayTNFs bind their physiological receptors

via MyGene.info

Gene · Ensembl

TNF receptor superfamily member 13B

Symbol
TNFRSF13B
Biotype
Protein coding
Organism
Homo sapiens
Location
17:16,929,816-16,972,118
Strand
Reverse (−)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Available in 6 languages

via Wikidata sitelinks · CC0