TNFRSF17

Also known as BCM, BCMA, CD269, TNFRSF13A, tumor necrosis factor receptor superfamily member 17, TNF receptor superfamily member 17

protein-coding gene in the species Homo sapiens

Gene data

TNFRSF17

Name: TNF receptor superfamily member 17
Type: protein-coding
Position: 11,965,138–11,968,068 (+)
Aliases: BCM, BCMA, CD269, TNFRSF13A
Ensembl: ENSG00000048462
RefSeq RNA: NM_001192.3
RefSeq protein: NP_001183.2

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. [provided by RefSeq, Jul 2008].