Structure via PubChem · Public domain (PubChem)
tolterodine
Sign in to saveAlso known as (+)-tolterodine, (+)-(R)-2-{alpha-[2-(diisopropylamino)ethyl]benzyl}-p-cresol
Tolterodine, sold under the brand name Detrol among others, is a medication used to treat frequent urination, urinary incontinence, or urinary urgency. Effects are seen within an hour. It is taken by mouth.
Key facts
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 470611677
- Drug.image
- Tolterodine.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 200
- Drug.tradename
- Detrol, Detrusitol, others
- Drug.MedlinePlus
- a699026
- Drug.DailyMedID
- Tolterodine
- Drug.pregnancy_AU
- B3
- Drug.routes_of_administration
- By mouth
- Drug.ATC_prefix
- G04
- Drug.ATC_suffix
- BD07
- Drug.legal_AU
- S4
- Drug.legal_CA
- Rx-only
- Drug.legal_UK
- POM
- Drug.legal_US
- Rx-only
- Drug.legal_EU
- Rx-only
- Drug.bioavailability
- 77%
via Wikipedia infobox
Chemical data
- Formula
- C22H31NO
- Molecular weight
- 325.5 g/mol
- IUPAC name
- 2-[(1R)-3-[di(propan-2-yl)amino]-1-phenylpropyl]-4-methylphenol
- SMILES
- CC1=CC(=C(C=C1)O)[C@H](CCN(C(C)C)C(C)C)C2=CC=CC=C2
- InChIKey
- OOGJQPCLVADCPB-HXUWFJFHSA-N
- XLogP
- 5.6
- Polar surface area
- 23.5 Ų
- H-bond donors
- 1
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
~3 min read
Encyclopedic overview
6 sectionsContents
- Medical uses
- Side effects
- Pharmacology
- Society and culture
- Brand names
- References
Tolterodine, sold under the brand name Detrol among others, is a medication used to treat frequent urination, urinary incontinence, or urinary urgency. Effects are seen within an hour. It is taken by mouth.
Common side effects include headache, dry mouth, constipation, and dizziness. Serious side effects may include angioedema, urinary retention, and QT prolongation. Use in pregnancy and breastfeeding are of unclear safety. It works by blocking muscarinic receptors in the bladder thus decreasing bladder contractions.
Excerpted from Wikipedia’s “tolterodine” article, available under the CC BY-SA 4.0 licence.