TOM1
Sign in to saveAlso known as target of myb1 membrane trafficking protein, IMD85
Target of Myb protein 1 is a protein that in humans is encoded by the TOM1 gene.
In the Vinony graph
Vinony's link graph records 7 inbound references to TOM1, and connects out to PubMed, human chromosome 22 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 22.
Vinony links it to 6 Wikipedia language editions.
Gene data
TOM1- Name
- target of myb1 membrane trafficking protein
- Type
- protein-coding
- Position
- 35,299,275–35,351,740 (+)
- Aliases
- IMD85
- Ensembl
- ENSG00000100284
- RefSeq RNA
- NM_001135729.2, NM_001135730.2, NM_001135732.2, NM_005488.3, NR_024194.2
- RefSeq protein
- NP_001129201.1, NP_001129202.1, NP_001129204.1, NP_005479.1, XP_011528120.1
This gene was identified as a target of the v-myb oncogene. The encoded protein shares its N-terminal domain in common with proteins associated with vesicular trafficking at the endosome. It is recruited to the endosomes by its interaction with endofin. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
target of myb1 membrane trafficking protein
- Symbol
- TOM1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 22:35,299,275-35,351,740
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein TOM1 PDB 1elk.png
Show 8 more facts
- HomoloGene ID
- 88453
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/10043
- genomic end
- 35347992
- genomic start
- 35695268
- chromosome
- human chromosome 22
- cytogenetic location
- 22q12.3
- Commons category
- TOM1
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Interactions
- References
- Further reading
- External links
Target of Myb protein 1 is a protein that in humans is encoded by the TOM1 gene.
The specific function of this gene has not yet been determined, yet it may involve the translocation of growth factor receptor complexes to the lysosome for degradation. This gene is localized to 22q13.1, with HMOX1 and MCM5 distally and HMG2L1 proximally positioned.
Excerpted from Wikipedia’s “TOM1” article, available under the CC BY-SA 4.0 licence.