MYBL2

Name

MYB proto-oncogene like 2

Type

protein-coding

Aliases

B-MYB, BMYB

The protein encoded by this gene, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. The encoded protein is phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2013].

via MyGene.info

Wikidata facts

Image

Protein MYBL2 PDB 1a5j.png

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