Also known as transketolase-2, transketolase-like protein 1, transketolase-related protein, TKTL1, TK 2, Transketolase 2
Transketolase-like-1 (TKTL1) is a gene closely related to the transketolase gene (TKT). It emerged in mammals during the course of evolution and, according to the latest research findings, is considered one of the key genes that distinguishes modern humans (Homo sapiens) from Neanderthals. However, some modern humans also exhibit the "archaic" transketolase-like-1 allele attributed to Neanderthals, with no known effects.
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).