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GeneQ17914031· pop 5· linked from 5 articles

Also known as DNAS1L1, DNASEX, DNL1L, G4.8, XIB, deoxyribonuclease I-like 1, deoxyribonuclease 1 like 1

Deoxyribonuclease-1-like 1 is an enzyme that in humans is encoded by the DNASE1L1 gene. It is also known as DNaseX due to its localisation on the X chromosome.

Gene data

DNASE1L1
Name
deoxyribonuclease 1 like 1
Type
protein-coding
Chromosome
X
Aliases
DNAS1L1, DNASEX, DNL1L, G4.8, XIB

This gene encodes a deoxyribonuclease protein that shows high sequence similarity to DNase I. The encoded protein is localized to the endoplasmic reticulum and modified by N-linked glycosylation. Alternate transcriptional splice variants encoding the same protein have been observed. [provided by RefSeq, Jan 2015].

via MyGene.info

Gene · Ensembl

deoxyribonuclease 1 like 1

Symbol
DNASE1L1
Biotype
Protein coding
Organism
Homo sapiens
Location
Chr X:154,401,236-154,412,119
Strand
Reverse (−)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Show 5 more facts
HomoloGene ID
4896
genomic start
154401236
genomic end
153640449
cytogenetic location
Xq28
Sources (4)

via Wikidata · CC0

~4 min read

Article

4 sections
Contents
  • Importance
  • Clinical application
  • References
  • Further reading

Deoxyribonuclease-1-like 1 is an enzyme that in humans is encoded by the DNASE1L1 gene. It is also known as DNaseX due to its localisation on the X chromosome.

This gene encodes a member of the deoxyribonuclease family and the protein and DNA shows high sequence similarity to lysosomal DNase I. Alternate transcriptional splice variants, encoding the same protein, have been characterized.

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