tricetin
Sign in to saveAlso known as 3',4',5,5',7-pentahydroxyflavone, 5,7-DIHYDROXY-2-(3,4,5-TRIHYDROXYPHENYL)-4H-CHROMEN-4-ONE
Tricetin is a flavone, a type of flavonoid. It is a rare aglycone found in the pollen of members of the Myrtaceae, subfamily Leptospermoideae, such as Eucalyptus globulus. This compound shows anticancer effects on human breast adenocarcinoma MCF-7 cells. Moreover. a potent anti-inflammatory effect of tricetin has also been demonstrated in a model of acute pancreatitis. This observation was explained by the compound's radical scavenging effects, its inhibitory effect on the DNA damage sensor enzyme poly (ADP-ribose) polymerase-1 (PARP1) and PARP1-mediated cell death and suppression of inflammat
Wikidata facts
- Subclass of
- flavone
- Mass
- 302.043
Show 5 more facts
- canonical SMILES
- C1=C(C=C(C(=C1O)O)O)C2=CC(=O)C3=C(C=C(C=C3O2)O)O
- chemical formula
- C₁₅H₁₀O₇
- found in taxon
- Larix sibirica
- has characteristic
- bitterness
- Commons category
- Tricetin
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Encyclopedic overview
2 sectionsContents
- See also
- References
Tricetin is a flavone, a type of flavonoid. It is a rare aglycone found in the pollen of members of the Myrtaceae, subfamily Leptospermoideae, such as Eucalyptus globulus. This compound shows anticancer effects on human breast adenocarcinoma MCF-7 cells. Moreover. a potent anti-inflammatory effect of tricetin has also been demonstrated in a model of acute pancreatitis. This observation was explained by the compound's radical scavenging effects, its inhibitory effect on the DNA damage sensor enzyme poly (ADP-ribose) polymerase-1 (PARP1) and PARP1-mediated cell death and suppression of inflammatory gene expression.
== See also == Tricin synthase produces tricin or tricetin 3′,5′-dimethyl ether Tricetin 3′,4′,5′-O-trimethyltransferase
Excerpted from Wikipedia’s “tricetin” article, available under the CC BY-SA 4.0 licence.