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triclofos

Structure via PubChem · Public domain (PubChem)

EntityQ15305564· pop 11· linked from 679 articles

Triclofos (brand names Triclos, Pedicloryl) is a sedative drug used rarely for treating insomnia.

Chemical data

Formula
C2H4Cl3O4P
Molecular weight
229.38 g/mol
IUPAC name
2,2,2-trichloroethyl dihydrogen phosphate

via PubChem

Drug data · ChEMBL

Max clinical phase
Approved
Molecule type
Small molecule
First approval
1982
Admin. routes
oral

via ChEMBL · EBI

~1 min read

Encyclopedic overview

2 sections
Contents
  • Side effects
  • References

Triclofos (brand names Triclos, Pedicloryl) is a sedative drug used rarely for treating insomnia.

Triclofos is a prodrug which is metabolised in the liver into the active drug trichloroethanol. The half-life of triclofos is fairly long and it may cause drowsiness the next day. Trichloroethanol may cause liver damage and triclofos should not be used for extended periods.

Excerpted from Wikipedia’s “triclofos” article, available under the CC BY-SA 4.0 licence.