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Structure via PubChem · Public domain (PubChem)
trolnitrate
Sign in to saveTrolnitrate (triethanolamine trinitrate, commonly used in the form of biphosphate salt also known as metamine) is an organic nitrate with vasodilator activity that is used to prevent or ameliorate attacks of angina pectoris. Trolnitrate dilates the coronary vessels because of its basic action as a smooth muscle depressant, just as do nitroglycerin and other organic nitrates.
Chemical data
- Formula
- C6H12N4O9
- Molecular weight
- 284.18 g/mol
- IUPAC name
- 2-[bis(2-nitrooxyethyl)amino]ethyl nitrate
- SMILES
- C(CO[N+](=O)[O-])N(CCO[N+](=O)[O-])CCO[N+](=O)[O-]
- InChIKey
- HWKQNAWCHQMZHK-UHFFFAOYSA-N
- XLogP
- 1.1
- Polar surface area
- 168 Ų
- H-bond donors
- 0
- H-bond acceptors
- 10
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- cardiovascular disease
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 284.06
Show 3 more facts
- canonical SMILES
- C(CO[N+](=O)[O-])N(CCO[N+](=O)[O-])CCO[N+](=O)[O-]
- chemical formula
- C₆H₁₂N₄O₉
- defined daily dose
- 20
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Trolnitrate (triethanolamine trinitrate, commonly used in the form of biphosphate salt also known as metamine) is an organic nitrate with vasodilator activity that is used to prevent or ameliorate attacks of angina pectoris. Trolnitrate dilates the coronary vessels because of its basic action as a smooth muscle depressant, just as do nitroglycerin and other organic nitrates.
==References==
Excerpted from Wikipedia’s “trolnitrate” article, available under the CC BY-SA 4.0 licence.