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Structure via PubChem · Public domain (PubChem)
benziodarone
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Chemical data
- Formula
- C17H12I2O3
- Molecular weight
- 518.08 g/mol
- IUPAC name
- (2-ethyl-1-benzofuran-3-yl)-(4-hydroxy-3,5-diiodophenyl)methanone
- SMILES
- CCC1=C(C2=CC=CC=C2O1)C(=O)C3=CC(=C(C(=C3)I)O)I
- InChIKey
- CZCHIEJNWPNBDE-UHFFFAOYSA-N
- XLogP
- 5.6
- Polar surface area
- 50.4 Ų
- H-bond donors
- 1
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
Withdrawn- Max clinical phase
- Approved
- Molecule type
- Small molecule
- Indications
- cardiovascular disease
via ChEMBL · EBI
Research
113 papers- Benziodarone and 6-hydroxybenziodarone are potent and selective inhibitors of transthyretin amyloidogenesis.Bioorganic & medicinal chemistry · 2023
- Attenuation of LPS-Induced Lung Injury by Benziodarone via Reactive Oxygen Species Reduction.International journal of molecular sciences · 2023
- Development of Benziodarone Analogues with Enhanced Potency for Selective Binding to Transthyretin in Human Plasma.Journal of medicinal chemistry · 2024
- [Gout and benziodarone].Rein et foie, maladies de la nutrition; actualites · 1967
- [Benziodarone and metabolism].Therapeutische Umschau. Revue therapeutique · 1966
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 517.888
Show 3 more facts
- canonical SMILES
- CCC1=C(C2=CC=CC=C2O1)C(=O)C3=CC(=C(C(=C3)I)O)I
- chemical formula
- C₁₇H₁₂I₂O₃
- Commons category
- Benziodarone
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
Benziodarone is a vasodilator.
thumb|center|700px|Benziodaron synthesis: Bufeniode has the same aromatic substitution pattern.
Excerpted from Wikipedia’s “benziodarone” article, available under the CC BY-SA 4.0 licence.