VPS11
Sign in to saveAlso known as END1, PEP5, RNF108, hVPS11, HLD12, VPS11, CORVET/HOPS core subunit, VPS11 core subunit of CORVET and HOPS complexes
Vacuolar protein sorting-associated protein 11 homolog is a protein that in humans is encoded by the VPS11 gene.
Gene data
VPS11- Name
- VPS11 core subunit of CORVET and HOPS complexes
- Type
- protein-coding
- Aliases
- DYT32, END1, HLD12, HLD12; DYT32, PEP5, RNF108, hVPS11
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps11 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014].
via MyGene.info
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 6673
- exact match
- identifiers.org/ncbigene/55823
- genomic start
- 118938403
- genomic end
- 118952688
- cytogenetic location
- 11q23.3
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Article
4 sectionsContents
- Function
- Interactions
- References
- Further reading
Vacuolar protein sorting-associated protein 11 homolog is a protein that in humans is encoded by the VPS11 gene.
== Function ==