VPS45
Sign in to saveAlso known as H1, H1VPS45, SCN5, VPS45A, VPS45B, VPS54A, VSP45, VSP45A
Vacuolar protein sorting-associated protein 45 is a protein that in humans is encoded by the VPS45 gene.
Gene data
VPS45- Name
- vacuolar protein sorting 45 homolog
- Type
- protein-coding
- Aliases
- H1, H1VPS45, SCN5, VPS45A, VPS45B, VPS54A, VSP45, VSP45A
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec1 domain family, and shows a high degree of sequence similarity to mouse, rat and yeast Vps45. The exact function of this gene is not known, but its high expression in peripheral blood mononuclear cells suggests a role in trafficking proteins, including inflammatory mediators. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2013].
via MyGene.info
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 5250
- exact match
- identifiers.org/ncbigene/11311
- genomic start
- 150067279
- genomic end
- 150145329
- cytogenetic location
- 1q21.2
Sources (4)
via Wikidata · CC0
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Article
3 sectionsContents
- Function
- References
- Further reading
Vacuolar protein sorting-associated protein 45 is a protein that in humans is encoded by the VPS45 gene.
== Function ==