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GeneQ18036224· pop 5· linked from 3 articles

Also known as WD repeat domain 6, Trm734

WD repeat-containing protein 6 is a protein that in humans is encoded by the WDR6 gene.

Gene data

WDR6
Name
WD repeat domain 6
Type
protein-coding
Aliases
Trm734

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. The encoded protein interacts with serine/threonine kinase 11, and is implicated in cell growth arrest. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016].

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Wikidata facts

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HomoloGene ID
117682
genomic end
49053386
genomic start
49044495
cytogenetic location
3p21.31
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WD repeat-containing protein 6 is a protein that in humans is encoded by the WDR6 gene.

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is ubiquitously expressed in adult and fetal tissues.

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