ZNF16

Also known as HZF1, KOX9, zinc finger protein 16

Zinc finger protein 16 is a protein that in humans is encoded by the ZNF16 gene.

Gene data

ZNF16

Name: zinc finger protein 16
Type: protein-coding
Position: 144,930,358–144,950,888 (−)
Aliases: HZF1, KOX9
Ensembl: ENSG00000170631
RefSeq RNA: NM_001029976.3, NM_001413564.1, NM_001413565.1, NM_001413566.1, NM_001413567.1
RefSeq protein: NP_001025147.2, NP_001400493.1, NP_001400494.1, NP_001400495.1, NP_001400496.1

The protein encoded by this gene contains multiple tandem zinc finger motifs. The encoded protein is involved in the differentiation of erythroid and megakaryocytic cells. This gene is located in a cluster of related genes on chromosome 8 encoding zinc finger proteins. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2012].

Gene Ontology

Biological process

regulation of transcription by RNA polymerase II positive regulation of cell population proliferation positive regulation of kinase activity negative regulation of apoptotic process positive regulation of erythrocyte differentiation positive regulation of megakaryocyte differentiation regulation of multicellular organismal process cellular response to sodium dodecyl sulfate

Molecular function

RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific protein binding

Cellular component

nucleus nucleus nucleus nucleoplasm nucleoplasm nucleolus

via MyGene.info

Gene · Ensembl

zinc finger protein 16

Symbol: ZNF16
Biotype: Protein coding
Organism: Homo sapiens
Location: 8:144,929,355-144,950,888
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Show 5 more facts

HomoloGene ID: 56008
exact match: identifiers.org/ncbigene/7564
genomic end: 146176274
genomic start: 146155744
cytogenetic location: 8q24.3

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Zinc finger protein 16 is a protein that in humans is encoded by the ZNF16 gene.

The protein encoded by this gene contains a Cys2His2 type of zinc finger, and thus may function as a transcription factor. This gene is located in a region close to ZNF7/KOX4, a gene also encoding a zinc finger protein, on chromosome 8. Two alternatively spliced variants, encoding the same protein, have been identified.