2,6-Diacetylpyridine is an organic compound with the formula C5H3N(C(O)CH3)2. It is a white solid that is soluble in organic solvents. It is a disubstituted pyridine. It is a precursor to ligands in coordination chemistry.
2,6-Diacetylpyridine is an organic compound with the formula C5H3N(C(O)CH3)2. It is a white solid that is soluble in organic solvents. It is a disubstituted pyridine. It is a precursor to ligands in coordination chemistry.
==Synthesis== The synthesis of 2,6-diacetylpyridine begins with oxidation of the methyl groups in 2,6-lutidine to form dipicolinic acid. This process has been well established with potassium permanganate and selenium dioxide. The diketone can be formed from the diester of picolinic acid groups through a Claisen condensation. The resulting adduct can be decarboxylated to give diacetylpyridine. center|650px|DAP synthesis Claisen
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).