Structure via PubChem · Public domain (PubChem)
2-Methyl-MDA
Sign in to saveAlso known as 2-Methyl-3,4-methylenedioxyamphetamine
2-Methyl-3,4-methylenedioxyamphetamine (2-methyl-MDA) is an entactogen-related drug of the amphetamine class. It acts as a selective serotonin releasing agent (SSRA), with IC50 values of 93nM, 12,000nM, and 1,937nM for serotonin, dopamine, and norepinephrine efflux. 2-Methyl-MDA is more potent than MDA and 5-methyl-MDA. However, it is slightly more selective for serotonin over dopamine and norepinephrine release in comparison to 5-methyl-MDA.
Chemical data
- Formula
- C11H15NO2
- Molecular weight
- 193.24 g/mol
- IUPAC name
- 1-(4-methyl-1,3-benzodioxol-5-yl)propan-2-amine
- SMILES
- CC1=C(C=CC2=C1OCO2)CC(C)N
- InChIKey
- WVACHJAKQMSYSU-UHFFFAOYSA-N
- XLogP
- 1.9
- Polar surface area
- 44.5 Ų
- H-bond donors
- 1
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 193.110279
Show 3 more facts
- chemical formula
- C₁₁H₁₅NO₂
- canonical SMILES
- CC1=C(C=CC2=C1OCO2)CC(C)N
- Commons category
- 2-Methyl-MDA
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- See also
- References
- External links
2-Methyl-3,4-methylenedioxyamphetamine (2-methyl-MDA) is an entactogen-related drug of the amphetamine class. It acts as a selective serotonin releasing agent (SSRA), with IC50 values of 93nM, 12,000nM, and 1,937nM for serotonin, dopamine, and norepinephrine efflux. 2-Methyl-MDA is more potent than MDA and 5-methyl-MDA. However, it is slightly more selective for serotonin over dopamine and norepinephrine release in comparison to 5-methyl-MDA.
== See also == Substituted methylenedioxyphenethylamine 2,6-di-tert-butylphenol
Excerpted from Wikipedia’s “2-Methyl-MDA” article, available under the CC BY-SA 4.0 licence.