Antagonista 5-HT3

Also known as 5HT3 antagonist, 5-HT3 antagonists, setron, setrons, Serotonin 5-HT3 Receptor Antagonists, 5-HT3 Antagonists, 5-HT3 Antagonist, 5-HT3 receptor antagonists

Research

10,029 papers

5-HT3 receptors.Current pharmaceutical design · 2006
Chemotherapy-Induced Nausea and Vomiting: Pathogenesis, Recommendations, and New Trends.Cancer treatment and research communications · 2021
Combination of 5-HT3 Antagonist and Dexamethasone Is Superior to 5-HT3 Antagonist Alone for PONV Prophylaxis After Laparoscopic Surgeries: A Meta-analysis.Anesthesia and analgesia · 2016
Olanzapine combined with 5-hydroxytryptamine type 3 receptor antagonist (5-HT3 RA) plus dexamethasone for prevention and treatment of chemotherapy-induced nausea and vomiting in high and moderate emetogenic chemotherapy: a systematic review and meta-analysis of randomised controlled trials.ESMO open · 2020
Granisetron, a selective 5-HT3 antagonist, reduces L-3,4-dihydroxyphenylalanine-induced abnormal involuntary movements in the 6-hydroxydopamine-lesioned rat.Behavioural pharmacology · 2021

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Wikidata facts

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Article · Português

Os antagonistas 5-HT3, informalmente conhecidos como "setrons", são uma que atuam como antagonistas de receptores no receptor 5-HT3, um subtipo de receptor de serotonina encontrado em terminais do nervo vago e em certas áreas do cérebro. Com as notáveis exceções de alossetrona e cilansetrona, os quais são usados no tratamento da síndrome do cólon irritável, todos os antagonistas 5-HT3 são antieméticos, usados na prevenção e tratamento de náusea e vômito. São particularmente efetivos em controlar a náusea e vômito produzidos por quimioterapia do câncer e são considerados o “padrão ouro” para este propósito.

Abstract from DBpedia / Wikipedia · CC BY-SA