5-hydroxytryptamine receptor 1B
Sign in to saveAlso known as S12, serotonin receptor 1B, serotonin 1D beta receptor, HTR1B, 5-HT-1D-beta, 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled, serotonin 1B receptor
mammalian protein found in Homo sapiens
Protein · UniProt
5-hydroxytryptamine receptor 1B
- Gene
- HTR1B
- Organism
- Homo sapiens (Human)
- Length
- 390 aa
- Molecular mass
- 43,568 Da
- Evidence
- 1: Evidence at protein level
G protein-coupled receptor for 5-hydroxytryptamine (serotonin) (PubMed:10452531, PubMed:1315531, PubMed:1328844, PubMed:1348246, PubMed:1351684, PubMed:1559993, PubMed:1565658, PubMed:1610347, PubMed:23519210, PubMed:23519215, PubMed:29925951, PubMed:8218242). Also functions as a receptor for ergot alkaloid derivatives, various anxiolytic and antidepressant drugs and other psychoactive substances, such as lysergic acid diethylamide (LSD) (PubMed:23519210, PubMed:23519215, PubMed:29925951). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding pro…
Swiss-Prot (reviewed) · via UniProt
Clinical Trials
1 registered- PHASE1/PHASE2RECRUITINGPhase 1b/2a Clinical Trial to Determine the Safety, Tolerability and Efficacy of TZ-161 in Spinal Cord InjuryTechnophage, SA · NCT06677229
Wikidata facts
- Instance of
- protein
Show 4 more facts
- cell component
- dendrite
- physically interacts with
- rizatriptan
- found in taxon
- Homo sapiens
- exact match
- purl.uniprot.org/uniprot/P28222
via Wikidata · CC0