Structure via PubChem · Public domain (PubChem)
CP 93129
Sign in to saveAlso known as CP-93,129, CP-93129, CP93129
CP-93129 is a drug which acts as a potent and selective serotonin 5-HT1B receptor agonist, with approximately 150-fold and 200-fold selectivity over the closely related serotonin 5-HT1D and 5-HT1A receptors. It is used in the study of 5-HT1B receptors in the brain, particularly their role in modulating the release of other neurotransmitters. It produces antiaggressive effects in rodents.
Chemical data
- Formula
- C12H13N3O
- Molecular weight
- 215.25 g/mol
- IUPAC name
- 3-(1,2,3,6-tetrahydropyridin-4-yl)-1,4-dihydropyrrolo[3,2-b]pyridin-5-one
- SMILES
- C1CNCC=C1C2=CNC3=C2NC(=O)C=C3
- InChIKey
- PJYVGMRFPFNZCT-UHFFFAOYSA-N
- XLogP
- -0.1
- Polar surface area
- 56.9 Ų
- H-bond donors
- 3
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
142 papersvia PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 215.105862
Show 5 more facts
- chemical formula
- C₁₂H₁₃N₃O
- Commons category
- CP-93129
- canonical SMILES
- C1CNCC=C1C2=CNC3=C2NC(=O)C=C3
- subject has role
- serotonin receptor agonists
- physically interacts with
- 5-hydroxytryptamine receptor 1A
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
CP-93129 is a drug which acts as a potent and selective serotonin 5-HT1B receptor agonist, with approximately 150-fold and 200-fold selectivity over the closely related serotonin 5-HT1D and 5-HT1A receptors. It is used in the study of 5-HT1B receptors in the brain, particularly their role in modulating the release of other neurotransmitters. It produces antiaggressive effects in rodents.
==See also== Serotonin 5-HT1B receptor agonist Cyclized tryptamine
Excerpted from Wikipedia’s “CP 93129” article, available under the CC BY-SA 4.0 licence.