fluprazine
Sign in to saveFluprazine (developmental code name DU-27,716) is a drug of the phenylpiperazine family. It is a so-called serenic or antiaggressive agent. It is closely related to several other piperazines, including eltoprazine and batoprazine, and TFMPP, as well as more distantly to the azapirones such as buspirone. The pharmacology of fluprazine is unknown, but it is likely to act as an agonist at the 5-HT1A and 5-HT1B receptors like its sister compound eltoprazine.
Research
33 papers- Specific anti-aggressive effects of fluprazine hydrochloride.Psychopharmacology · 1985
- Serenics fluprazine (DU 27716) and eltoprazine (DU 28853) enhance neophobic and emotional behaviour in mice.Psychopharmacology · 1990
- Fluprazine hydrochloride decreases copulation in male rats.Pharmacology, biochemistry, and behavior · 1985
- Fluprazine hydrochloride: no influence on the odor detection performance of male rats.Pharmacology, biochemistry, and behavior · 1990
- Fluprazine hydrochloride does not decrease defensive behaviors of wild and septal syndrome rats.Physiology & behavior · 1985
via PubMed
Wikidata facts
- Mass
- 316.151
Show 3 more facts
- chemical formula
- C₁₄H₁₉F₃N₄O
- canonical SMILES
- C1CN(CCN1CCNC(=O)N)C2=CC=CC(=C2)C(F)(F)F
- Commons category
- Fluprazine
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Article
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- References
Fluprazine (developmental code name DU-27,716) is a drug of the phenylpiperazine family. It is a so-called serenic or antiaggressive agent. It is closely related to several other piperazines, including eltoprazine and batoprazine, and TFMPP, as well as more distantly to the azapirones such as buspirone. The pharmacology of fluprazine is unknown, but it is likely to act as an agonist at the 5-HT1A and 5-HT1B receptors like its sister compound eltoprazine.
== See also == Substituted phenylpiperazine List of investigational aggression drugs