Structure via PubChem · Public domain (PubChem)
Chemical data
- Formula
- C24H24N2O4
- Molecular weight
- 404.5 g/mol
- IUPAC name
- propan-2-yl 4-(methoxymethyl)-6-phenylmethoxy-9H-pyrido[3,4-b]indole-3-carboxylate
- SMILES
- CC(C)OC(=O)C1=NC=C2C(=C1COC)C3=C(N2)C=CC(=C3)OCC4=CC=CC=C4
- InChIKey
- RLFKILXOLJVUNF-UHFFFAOYSA-N
- XLogP
- 4.4
- Polar surface area
- 73.4 Ų
- H-bond donors
- 1
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
137 papers- Abecarnil shows reduced tolerance development and dependence potential in comparison to diazepam: animal studies.Psychopharmacology series · 1993
- Nonsedating anxiolytics.Pharmacology, biochemistry, and behavior · 2024
- Abecarnil and alprazolam reverse anxiety-like behaviors induced by ethanol withdrawal.Alcohol (Fayetteville, N.Y.) · 2000
- Pharmacological evidence for full agonist activity of abecarnil at certain GABAA receptors.Psychopharmacology series · 1993
- Abecarnil enhances GABA-induced currents in acutely isolated cerebellar Purkinje cells.Neuropharmacology · 1995
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 404.174
Show 4 more facts
- World Health Organisation international non-proprietary name
- 阿贝卡尔
- subject has role
- anticonvulsant agent
- chemical formula
- C₂₄H₂₄N₂O₄
- canonical SMILES
- CC(C)OC(=O)C1=NC=C2C(=C1COC)C3=C(N2)C=CC(=C3)OCC4=CC=CC=C4
Sources (2)
via Wikidata · CC0