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aceclofenac
Sign in to saveAlso known as 2-[(2',6'-dichlorophenyl)amino]phenylacetoxyacetic acid, 2-[(2,6-dichlorophenyl)amino]phenylacetoxyacetic acid, PR-82/3, glycolic acid [o-(2,6-dichloroanilino)phenyl]acetate ester, 2-[(2,6-dichlorophenyl)amino]benzeneacetic acid carboxymethyl ester, Aceclofenacum, acéclofénac
Aceclofenac is a nonsteroidal anti-inflammatory drug (NSAID) analog of diclofenac. It is used for the relief of pain and inflammation in rheumatoid arthritis, osteoarthritis and ankylosing spondylitis.
Chemical data
- Formula
- C16H13Cl2NO4
- Molecular weight
- 354.2 g/mol
- IUPAC name
- 2-[2-[2-(2,6-dichloroanilino)phenyl]acetyl]oxyacetic acid
- SMILES
- C1=CC=C(C(=C1)CC(=O)OCC(=O)O)NC2=C(C=CC=C2Cl)Cl
- InChIKey
- MNIPYSSQXLZQLJ-UHFFFAOYSA-N
- XLogP
- 4.3
- Polar surface area
- 75.6 Ų
- H-bond donors
- 2
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Research
571 papers- Aceclofenac.2006
- Aceclofenac and methotrexate combination therapy could influence Th1/Th17 axis to modulate rheumatoid-arthritis-induced inflammation.Drug discovery today · 2023
- Aceclofenac: a reappraisal of its use in the management of pain and rheumatic disease.Drugs · 2001
- A Review of Aceclofenac: Analgesic and Anti-Inflammatory Effects on Musculoskeletal Disorders.Journal of pain research · 2021
- Aceclofenac in the management of inflammatory pain.Expert opinion on pharmacotherapy · 2004
via PubMed
~3 min read
Encyclopedic overview
9 sectionsContents
- Side effects
- Chemistry
- Society and culture
- Economics
- Brand names
- References
- Citations
- General and cited sources
- External links
Aceclofenac is a nonsteroidal anti-inflammatory drug (NSAID) analog of diclofenac. It is used for the relief of pain and inflammation in rheumatoid arthritis, osteoarthritis and ankylosing spondylitis.
It was patented in 1983 and approved for medical use in 1992.
Excerpted from Wikipedia’s “aceclofenac” article, available under the CC BY-SA 4.0 licence.