acemetacin
Sign in to saveAlso known as TV-1322, TVX 3322, K-708, K 708, indometacin carboxymethyl ester, indomethacin carboxymethyl ester, indometacin glycolic ester, indomethacin glycolic ester
Acemetacin is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of osteoarthritis, rheumatoid arthritis, lower back pain, and relieving post-operative pain. It is manufactured by Merck KGaA under the tradename Emflex. It is no longer available in the UK (since 2018), however is available in other countries as a prescription-only drug.
Research
156 papers- Acemetacin.2006
- Single dose oral acemetacin for acute postoperative pain in adults.The Cochrane database of systematic reviews · 2009
- Acemetacin monohydrate.Acta crystallographica. Section C, Crystal structure communications · 2007
- Non-steroidal anti-inflammatory drugs (NSAIDs), pain and aging: Adjusting prescription to patient features.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022
- Radioiodinated acemetacin loaded niosomes as a dual anticancer therapy.International journal of pharmaceutics · 2022
via PubMed
Wikidata facts
- Mass
- 415.082
Show 4 more facts
- chemical formula
- C₂₁H₁₈ClNO₆
- canonical SMILES
- CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)OCC(=O)O
- World Health Organisation international non-proprietary name
- acemetacin
- Commons category
- Acemetacin
Sources (2)
via Wikidata · CC0
~5 min read
Article
10 sectionsContents
- Medical uses
- Contraindications
- Adverse effects
- Interactions
- Pharmacology
- Pharmacokinetics
- Chemistry
- Society and culture
- Brand names
- References
Acemetacin is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of osteoarthritis, rheumatoid arthritis, lower back pain, and relieving post-operative pain. It is manufactured by Merck KGaA under the tradename Emflex. It is no longer available in the UK (since 2018), however is available in other countries as a prescription-only drug.
== Medical uses == Acemetacin has proven effective in the treatment of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and other kinds of rheumatoid inflammation, as well as in post-operative and post-traumatic pain and attack of gout. Application of a single dose of acemetacin for post-operative pain is not well supported by studies.