Structure via PubChem · Public domain (PubChem)
acefylline
Sign in to saveAcefylline (INN), also known as 7-theophyllineacetic acid, is a stimulant drug of the xanthine chemical class. It acts as an adenosine receptor antagonist. It is combined with diphenhydramine in the pharmaceutical preparation etanautine to help offset diphenhydramine induced drowsiness.
Chemical data
- Formula
- C9H10N4O4
- Molecular weight
- 238.2 g/mol
- IUPAC name
- 2-(1,3-dimethyl-2,6-dioxopurin-7-yl)acetic acid
- SMILES
- CN1C2=C(C(=O)N(C1=O)C)N(C=N2)CC(=O)O
- InChIKey
- HCYFGRCYSCXKNQ-UHFFFAOYSA-N
- XLogP
- -0.8
- Polar surface area
- 95.7 Ų
- H-bond donors
- 1
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Mass
- 238.07
Show 6 more facts
- chemical formula
- C₉H₁₀N₄O₄
- canonical SMILES
- CN1C2=C(C(=O)N(C1=O)C)N(C=N2)CC(=O)O
- medical condition treated
- bronchitis
- melting point
- 270.0
- found in taxon
- Pogostemon cablin
- Commons category
- Acefylline
Sources (6)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
Acefylline (INN), also known as 7-theophyllineacetic acid, is a stimulant drug of the xanthine chemical class. It acts as an adenosine receptor antagonist. It is combined with diphenhydramine in the pharmaceutical preparation etanautine to help offset diphenhydramine induced drowsiness.
A silanol–mannuronic acid conjugate of acefylline, acefylline methylsilanol mannuronate (INCI; trade name Xantalgosil C) is marketed as a lipolytic phosphodiesterase inhibitor. It is used as an ingredient in cosmeceuticals for the treatment of cellulite and as a skin conditioner.
Excerpted from Wikipedia’s “acefylline” article, available under the CC BY-SA 4.0 licence.
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