File:Aciclovir_2D_structure.svg · Wikimedia Commons · See Wikimedia Commons
اسیکلوویر
Sign in to saveAlso known as acyclovir, acycloguanosine, zovirax, ACV
OverviewAI-generated
Aciclovir is a chemical compound with the formula C₈H₁₁N₅O₃. Its IUPAC name is 2-amino-9-(2-hydroxyethoxymethyl)-1H-purin-6-one. The substance has a mass of 225.086 and a weight of 225.20. It possesses a charge of 0, an xlogp of -1.9, and a tpsa of 115. The molecule contains 3 hydrogen bond donors and 5 hydrogen bond acceptors.
The compound is associated with a price of 0.151. It is referenced by 243 other encyclopedia articles. A search for aciclovir in PubMed yields a count of 20537 entries.
Synthesized by Vinony from 18 facts across 4 sources: Wikidata, PubMed, PubChem, Vinony graph. Generated from structured data (not the Wikipedia text) and checked against those facts — may still contain errors.
Chemical data
- Formula
- C8H11N5O3
- Molecular weight
- 225.2 g/mol
- IUPAC name
- 2-amino-9-(2-hydroxyethoxymethyl)-1H-purin-6-one
- SMILES
- C1=NC2=C(N1COCCO)N=C(NC2=O)N
- InChIKey
- MKUXAQIIEYXACX-UHFFFAOYSA-N
- XLogP
- -1.9
- Polar surface area
- 115 Ų
- H-bond donors
- 3
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1982
- Admin. routes
- oral, parenteral, topical
- Indications
- Herpes Zoster, chickenpox, genital herpes, viral disease
via ChEMBL · EBI
Research
20,537 papers- Aciclovir-induced neurotoxicity.Practical neurology · 2023
- Aciclovir prophylaxis after varicella zoster exposure in pregnancy.Drug and therapeutics bulletin · 2023
- Aciclovir-resistant herpes keratitis.Clinical & experimental ophthalmology · 2010
- Encephalitis--beyond aciclovir.Advances in experimental medicine and biology · 2004
- Neonatal varicella.Archives of disease in childhood · 2024
via PubMed
Wikidata facts
- Subclass of
- nucleoside analogue
- Mass
- 225.086
- Has use
- medication
Show 7 more facts
- chemical formula
- C₈H₁₁N₅O₃
- Commons category
- Aciclovir
- canonical SMILES
- C1=NC2=C(N1COCCO)NC(=NC2=O)N
- subject has role
- antiviral drug
- price
- 0.151
- found in taxon
- Epicoccum nigrum
- significant drug interaction
- foscarnet
Sources (7)
via Wikidata · CC0