acrosin
Sign in to saveAlso known as preproacrosin, acrosin light and heavy chain prepropeptide, ACR, proacrosin, uniprot:P10323
Acrosin is a digestive enzyme that acts as a protease. In humans, acrosin is encoded by the ACR gene. Acrosin is released from the acrosome of spermatozoa as a consequence of the acrosome reaction. It aids in the penetration of the Zona Pellucida.
Key facts
- Enzyme.Name
- Acrosin
- Enzyme.EC_number
- 3.4.21.10
- Enzyme.CAS_number
- 9068-57-9
- Enzyme.GO_code
- 0004284
- Enzyme.image
- 1FIW.png
via Wikipedia infobox
Protein · UniProt
Acrosin
- Gene
- ACR
- Organism
- Homo sapiens (Human)
- Length
- 421 aa
- Molecular mass
- 45,847 Da
- Evidence
- 1: Evidence at protein level
Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome
Swiss-Prot (reviewed) · via UniProt
Wikidata facts
- Instance of
- protein
- Image
- 1FIW.png
Show 4 more facts
- exact match
- purl.uniprot.org/uniprot/P10323
- biological process
- protein catabolic process
- found in taxon
- Homo sapiens
- Commons category
- Acrosin
via Wikidata · CC0
~7 min read
Encyclopedic overview
7 sectionsContents
- Enzyme Mechanism
- Biological Function
- Structure
- Disease and Pharmaceutical Relevance
- References
- Further reading
- External links
Acrosin is a digestive enzyme that acts as a protease. In humans, acrosin is encoded by the ACR gene. Acrosin is released from the acrosome of spermatozoa as a consequence of the acrosome reaction. It aids in the penetration of the Zona Pellucida.
== Enzyme Mechanism == Acrosin is a typical serine proteinase with trypsin-like specificity.
Excerpted from Wikipedia’s “acrosin” article, available under the CC BY-SA 4.0 licence.