Streptokinase
Sign in to saveAlso known as Streptase, Kabikinase, Streptokinase C precursor
Streptokinase is a thrombolytic medication activating plasminogen by nonenzymatic mechanism. As a medication it is used to break down clots in some cases of myocardial infarction (heart attack), pulmonary embolism, and arterial thromboembolism. The type of heart attack it is used in is an ST elevation myocardial infarction (STEMI). It is given by injection into a vein.
Key facts
- Drug.image
- Sk surface 3.png
- Drug.caption
- Complex of catalytic domain of human plasmin and streptokinase
- Drug.tradename
- Fibrion
- Drug.routes_of_administration
- Intravenous
- Drug.ATC_prefix
- B01A
- Drug.ATC_suffix
- D01
- Drug.CAS_number
- 9002-01-1
- Drug.DrugBank
- DB00086
- Drug.ChemSpiderID
- none
- Drug.UNII
- 8X1OXL3SNU
- Drug.synonyms
- SK
- Drug.C
- 2100
- Drug.H
- 3278
- Drug.N
- 566
- Drug.O
- 669
- Drug.S
- 4
- Nonhuman protein.Organism
- Streptococcus dysgalactiae subsp. equisimilis
- Nonhuman protein.Name
- Streptokinase C
via Wikipedia infobox
Wikidata facts
Show 3 more facts
- World Health Organisation international non-proprietary name
- streptokinase
- Commons category
- Streptokinase
- MCN code
- 3003.90.21
Sources (2)
via Wikidata · CC0
~7 min read
Article
11 sectionsContents
- Medical uses
- Contraindications
- Absolute
- Relative
- Mechanism of action
- Biology
- History
- Research
- Marketing
- References
- External links
Streptokinase is a thrombolytic medication activating plasminogen by nonenzymatic mechanism. As a medication it is used to break down clots in some cases of myocardial infarction (heart attack), pulmonary embolism, and arterial thromboembolism. The type of heart attack it is used in is an ST elevation myocardial infarction (STEMI). It is given by injection into a vein.
Side effects include nausea, bleeding, low blood pressure, and allergic reactions. A second use in a person's lifetime is not recommended. While no harm has been found with use in pregnancy, it has not been well studied in this group. Streptokinase is in the antithrombotic family of medications and works by turning on the fibrinolytic system.