ADCY2
Sign in to saveAlso known as AC2, HBAC2, adenylate cyclase 2 (brain), adenylate cyclase 2
Adenylyl cyclase type 2 is an enzyme typically expressed in the brain of humans, that is encoded by the ADCY2 gene. It belongs to the adenylyl cyclase class-3 or guanylyl cyclase family because it contains two guanylate cyclase domains. ADCY2 is one of ten different mammalian isoforms of adenylyl cyclases. ADCY2 can be found on chromosome 5 and the "MIR2113-POU3F2" region of chromosome 6, with a length of 1091 amino-acids. An essential cofactor for ADCY2 is magnesium; two ions bind per subunit.
Gene data
ADCY2- Name
- adenylate cyclase 2
- Type
- protein-coding
- Aliases
- AC2, HBAC2
This gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). This enzyme is insensitive to Ca(2+)/calmodulin, and is stimulated by the G protein beta and gamma subunit complex. [provided by RefSeq, Jul 2008].
via MyGene.info
Gene · Ensembl
adenylate cyclase 2
- Symbol
- ADCY2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 5:7,395,681-7,830,638
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein ADCY2 PDB 1ab8.png
Show 5 more facts
- HomoloGene ID
- 75133
- exact match
- identifiers.org/ncbigene/108
- genomic end
- 7830194
- genomic start
- 7396138
- cytogenetic location
- 5p15.31
via Wikidata · CC0
~3 min read
Article
7 sectionsContents
- Structure
- Function
- Clinical significance
- Interactive pathway map
- References
- External links
- Further reading
Adenylyl cyclase type 2 is an enzyme typically expressed in the brain of humans, that is encoded by the ADCY2 gene. It belongs to the adenylyl cyclase class-3 or guanylyl cyclase family because it contains two guanylate cyclase domains. ADCY2 is one of ten different mammalian isoforms of adenylyl cyclases. ADCY2 can be found on chromosome 5 and the "MIR2113-POU3F2" region of chromosome 6, with a length of 1091 amino-acids. An essential cofactor for ADCY2 is magnesium; two ions bind per subunit.
== Structure ==